Vascular Parkinsonism (VP)

Vascular parkinsonism (VP), performing from cerebrovascular complaint, is a rare complaint showing a variety of clinical and pathological donations distinct from sporadic Parkinson’s complaint (PD). It accounts for 3-6 of all parkinsonian runs, and is delicate to diagnose with clinical certainty. Clinical features include bilateral symmetrical severity; bradykinesia, generally involving lower branches; postural insecurity; shuffling gait; madness and corticospinal findings.Neuropathology shows multiple subcortical ischemic lesions owing to small vessel complaint in striatum Globus pallid us, white matter and, substantial nagar, involving cortico-striato-pallidal, thalamofrontal and other Circles, without substantiation of Lowy bodies. Cranial reckoned tomography and glamorous resonance imaging are useful tests to estimate the vascular lesions. Functional imaging of presynaptic dopamine transporter may be useful in the isolation of VP from PD. Response to levodopa treatment has been reported in over to 50 of VP cases,  particularly in those with lesions in or close to nigrostriatal pathways, although only a many  cases demonstrate long- term efficacity.

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